Dental occlusion refers to the static and dynamic relationship between the maxillary and mandibular teeth as they contact during functional and parafunctional activities. It plays a critical role in maintaining oral health, optimal mastication, neuromuscular balance, and temporomandibular joint (TMJ) stability. Proper occlusal relationships support efficient force distribution and contribute to the longevity of teeth and restorations, while malocclusion may lead to functional disturbances, periodontal stress, muscular dysfunction, and TMJ disorders. Contemporary understanding of occlusion integrates anatomical, biomechanics, and neuromuscular principles, emphasizing individualized patient assessment rather than a single ideal occlusal scheme. diagnostic accuracy and treatment planning. This abstract summarizes the foundational concepts, clinical implications, and evolving approaches in the study of dental occlusion.